The new website is easy to navigate, giving clear distinctions of instruments for both the Food Characterization Division and the Polymer Characterization Division. Each division has two unique search methods; the Polymer Characterization Division portion has a menu for looking up products by ‘application’ in addition to a more traditional ‘product’ menu, while the Food Characterization Division boasts a search by ‘industry’ segment in addition to its ‘product’ menu.

Take some time to peruse our new website and discover what C.W. Brabender® Instruments, Inc. can do to help you succeed in your R&D, Product Development and Quality Control endeavors.

This is Particle Sciences’ fourth extruder dedicated to drug/polymer combinations. According to Mark Mitchnick, Particle Sciences’ CEO, “The demand for cGMP extrusion is increasing. Needs range from hot melt extrusion for solid oral dosage forms to drug eluting devices. Particle Sciences is the leading CRO in this area having invested heavily in equipment, high potency compound handling infrastructure and proprietary modeling software. With injection molding, tube extrusion, coextrusion and the leading analytic support facility, we are working very hard to make sure our clients’ projects move as quickly as possible. In 2011 we successfully brought such products into the clinic and already have several scheduled for cGMP manufacturing in 2012. While there are several fine extruders on the market, Brabender® Pharma has focused their 12 mm on the pharmaceutical development space. Its ease of cleaning, full cGMP compliance and extensive data capture capabilities make it a valuable addition to rapid product development efforts.”

Kevin Van Allen, Brabender® Pharma’s V.P. of Sales & Marketing, adds “Particle Sciences is an innovative leader in pharmaceutical extrusion and we are very pleased to be working with them. With the placement of the Mini-Compounder at Particle Sciences, Brabender® Pharma clients will now have a US site for evaluation and development of their API’s from early stage and into cGMP production, including highly potent compounds. The 12 mm Mini-Compounder will be a truly valuable asset to Particle Sciences Inc. because its clamshell barrel, removable liner and segmented screw elements will offer numerous new processing capabilities to explore. As pharmaceutical extrusion processes are continually being refined, we feel that the 12 mm Mini-Compounder plus added co-extrusion capabilities will give PSI a world of future product development possibilities.”

THE DRIVE
A heavy-duty high torque system - the Prep-Mill® drive is designed to provide high torque output from a 2.5 HP sensor-less vector drive with built-in torque overload protection. Monitored by a digital DC amp meter with torque overload indicator, including a digital RPM indicator - variable roll speed of 0-30 RPM. There are dial gauges installed over the rolls to accurately determine the roll gap setting. In addition to the operator trip bar over the mill rolls, two operator 'kick plates' will also stop the drive when actuated. The 'kick plates' are permanently mounted on both sides of the mill. There is also an ‘emergency stop’ on top of the unit. A ‘Safety Guard’ is installed over the top of the rolls for added security. The entire drive is mounted on a heavy gauge mobile cart. The cart includes a cabinet for storage of tools and accessories.

FEATURES
The Electrically Heated Prep-Mill® utilizes improved transfer rolls coated with Acrotherm TK400 (RC 70), an extremely durable coating that substantially extends the life of the roll while providing top quality mirror finish and tolerances - suited for High Wear Resistance.

• Electrically Heated 4"x8" Acrotherm TK400 rolls polished to a mirror finish
• Individual Temperature Controllers to control roll temperature
• Adjustable gap from .005” to .195"
• Standard friction ratio of 1.3:1 or 1:1 for Calendering
• Safety trip bar and operator kick plates with coupled electrical interlock
• Contoured roll guides prevent material from 'creeping off' the rolls and into the bushings
• "Flip-up" design for easy cleaning
• Brass stripping knife permits quick, clean removal of milled stock
• A mixing volume of approximately 250ml, depending on gap setting and bandwidth
• ‘Safety Guard’ over the top of the rolls and dial gauges for accurate roll gap adjustment

The University Of Utah recently acquired the Mini-Compounder TSE 12/36, a 12mm Twin-Screw Extruder with a clamshell barrel and segmented screw elements, for testing and evaluation of Hot Melt Extrusion, Bioability and Solubility studies and have reported back outstanding results and response from the University’s Assoc. Prof. Patrick Kiser. As part of this initiative the University of Utah and C.W. Brabender® Instruments, Inc. have agreed to use the University’s facility as a West Coast laboratory for customer visits to review the instrument as well as run trials of their own materials to see the viability and benefits of this unit in their own testing.

C.W. Brabender® Instruments, Inc. is truly excited to be working with Assoc. Prof. Patrick Kiser of the University Of Utah and their outstanding Department of Bioengineering and Department of Pharmaceutics and Pharmaceutical Chemistry. “This instrument is a great unit and I truly love working with it because of its versatility in developing hot-melt controlled release dosage forms” stated Assoc. Prof. Patrick Kiser “and I look forward to sharing that experience with any and all interested industry personnel.”

The Taste Sensing System TS-5000Z employs the same mechanism as the human tongue through the use of multi-channel artificial lipid membrane sensors which imitate the taste reception of food goods and pharmaceuticals and interprets them as numerical data.  The quantification of taste data is handled via original algorithms and can be displayed in various ways through a rich array of graphing tools.  In addition to the evaluation of initial taste, the instrument also measures aftertaste – the persistent taste that remains in the mouth after food has been swallowed.  Even aspects of aftertaste such as “richness”, “sharpness”, “bitterness” and “astringency” can be measured.

C.W. Brabender® Instruments, Inc. is truly excited to bring this next evolution in taste sensory measurement to the North American, Central American and South American markets for use in a variety of fields including, but not limited to, Quality Control, Product Development, Marketing and Sales.  With more than 300 units already sold worldwide, we truly look forward to showing our territories the vast potential that this instrument has in both the food and pharmaceutical industries.

The advancements on the NEW Farinograph®-AT center around the automatic water dosing system which alleviates the potential for operator error during the addition of water to the flour in the mixer measuring head. The addition of an integrated 2 liter water tank to the fully redesigned housing of the drive unit give the instrument a new modern look and feel. The water tank is temperature controlled and simple to remove. The Farinograph®-AT now records the temperature of the dosing water in the water tank and the temperature of the dough in the mixing bowl. The torque range now reaches 20 Nm and the unit calculates the mixing energy during testing.

The expanded software takes full advantage of the variable speed (0 – 200 min^-1) of the drive and allows for programming of speed profiles and the creation of individual test profile that meet each test’s needs. The ability to define your own evaluation methods now makes the Farinograph®-AT one of the most flexible testing instruments available. The new model lends it to a plethora of special applications including chocolate, chewing gum, cheese, meat, fish, full formula dough and many more non-standard uses establishing its place in every food lab as a truly valuable and versatile testing tool.

Dr. Yan has brought many years of significant experience and expertise in cereal chemistry, food testing and new food product development to C.W. Brabender® Instruments, Inc.  Her higher educational background began with a B.S. in Grain and Oil Storage at Henan University of Technology (formerly Zhengzhou Grain College) in China.  She achieved her M.S. in Grain Science and Industry from Kansas State University and has completed her PhD in Biological and Agricultural Engineering on May 3, 2011 at Kansas State University in Manhattan, KS.

Dr. Shuping Yan is responsible for maintaining the C.W. Brabender® Food Laboratory while conducting research on our extensive line of laboratory scale food testing instruments.  She is responsible for publishing papers on her new research findings as well as handling all customer technical inquiries in support of our food instrument product line for the North American market.